Nk1.1

Natural killer cells (NK cells or) are a type of cytotoxic lymphocytes that constitute an important component of the innate immune system. NK cells play a major role in the rejection of tumors and cells infected by viruses. The cells kill by releasing small cytoplasmic granules of proteins called perforin and granzyme that cause the target cell to die by cell death.

NK cells are defined as large granular lymphocyte (LGL) and are the third kind of cells differentiated from the common ancestor of production lymphoid B and T lymphocytes They do not express antigen receptors of T cells (TCR) or Pan T marker CD3 or surface immunoglobulins (Ig) receptors on B cells, but they usually express the surface markers CD16 (Fc? RIII) and CD56 in the man, and NK1.1/NK1.2 in some strains of mice. Up to 80% of NK cells also express CD8.

They were named "natural killer" because of the initial notion that they do not require activation to kill cells that are missing "self" markers of major histocompatibility complex (MHC)

Natural killer cells (NK cells or) are a type of cytotoxic lymphocytes that constitute an important component of the innate immune system. NK cells play a major role in the rejection of tumors and cells infected by viruses. The cells kill by releasing small cytoplasmic granules of proteins called perforin and Granzyme causing target cell death by apoptosis.

NK cells are defined as large granular lymphocyte (LGL) and are the third type of cells differentiate from the common ancestor of production, and several B lymphoid T cells They do not express antigen receptors of T cells (TCRs) or Pan T marker CD3 or surface immunoglobulins (Ig) receptors on B cells, but they usually express the surface markers CD16 (Fc? RIII) and CD56 in the man, and NK1.1/NK1.2 in some strains of mice. Up to 80% of NK cells also express CD8.

They were named "natural killer" because of the initial notion that they do not require activation to kill cells that are missing "self" markers of major histocompatibility complex (MHC)